By plane
The closest commercial airports are John Wayne Airport, Santa Ana SNA followed by Long Beach Airport LGB, while the Los Angeles Interantional Airport LAX is the largest one in the area.
For those who rent a car or take a taxi, travel time from SNA is about 20-30 minutes, depending on traffic. From LAX, the trip takes about 45-60 minutes, depending on traffic. A taxi from SNA costs about $40; from LAX, about $70.
For most people who don't rent a car, shared shuttle van service, like SuperShuttle, is an economical option. The shuttle will make multiple stops, but you will be delivered right to the door of your hotel. From LAX, the cost is about $16 per person one way/$32 per person roundtrip, plus tip. From SNA, the cost is about $10 per person one way/$20 per person roundtrip, plus tip.
By train
Amtrak and Metrolink provide service at Anaheim Station, located at 2150 East Katella Avenue on the north side of Angel Stadium's parking lot, across from Honda Center, and 2.5 miles east of Disneyland. The station has a ticket office, enclosed waiting area, and restrooms. Amtrak's Pacific Surfliner Route (http://www.amtrak.com/ser...) services this station.
The transit connection to Disneyland is actually best at the Fullerton Amtrak/Metrolink station in the city's pleasant downtown area. From there it's just short a ride on OCTA line 43 to Disneyland.
You can also get to Disneyland on Metro bus 460 from Downtown Los Angeles, a semi-express bus that is a fairly slow but direct ride.
By car
It is right on the I-5 and can be reached from Los Angeles on the same road. In rush hour, it may be faster to use Route 91 even if it is longer as it is less congested.